A Nurse-Centered Socio-Technical Readiness Framework for Artificial Intelligence in Clinical Practice
DOI:
https://doi.org/10.65655/OpenChristianPress.2026.117Keywords:
nursing, Artificial intelligence, AI readiness, digital health, clinical decision support, socio-technical systems, nursing ethics, technology acceptance, patient safety, AI governanceAbstract
Background: Artificial intelligence (AI) is moving from experimental promise into the everyday infrastructure of clinical work through predictive analytics, clinical decision support, remote monitoring, documentation automation, robotics, and increasingly generative AI. Nurses are central to this transition because they translate data-rich systems into bedside decisions, relational care, safety surveillance, patient advocacy, and ethical accountability. Yet the literature shows that nurses’ AI preparedness remains uneven, with readiness shaped not only by literacy and training but also by workflow fit, explainability, professional autonomy, equity, and governance. Aim: This article develops a nurse-centered socio-technical framework for AI readiness in clinical practice and clarifies why preparing nurses for AI requires more than digital skills acquisition. Design: Critical integrative review and conceptual framework development. Evidence base: The synthesis integrates recent empirical nursing studies, systematic and qualitative reviews, nursing position statements, health AI reporting standards, and global AI governance guidance. Priority was given to peer-reviewed sources published from 2018 to 2026, supplemented by foundational theories of technology acceptance, socio-technical systems, nursing ethics, and human factors. Synthesis: Six interdependent readiness domains were identified: technical, educational, ethical/legal, professional, organizational, and equity/governance readiness. These domains explain why AI adoption may fail even when systems are technically sophisticated and why nurse participation in design, implementation, oversight, and evaluation is indispensable. Conclusion: AI readiness in nursing is best understood as a socio-technical capability distributed across persons, technologies, institutions, regulations, and moral relationships. AI should augment, not displace, the nurse’s clinical judgment, relational presence, and professional responsibility. Impact: The proposed framework offers nurse educators, clinical leaders, health system executives, AI developers, regulators, and researchers a practical structure for designing, evaluating, and governing AI-enabled nursing practice without weakening the human core of care.
References
American Academy of Nursing. (2026). American Academy of Nursing position statement on artificial intelligence in health care. Nursing Outlook. Advance online publication. https://www.nursingoutlook.org/article/S0029-6554(26)00098-9/fulltext
American Nurses Association. (2022). The ethical use of artificial intelligence in nursing practice. https://www.nursingworld.org/globalassets/practiceandpolicy/nursing-excellence/ana-position-statements/the-ethical-use-of-artificial-intelligence-in-nursing-practice_bod-approved-12_20_22.pdf
Ajzen, I. (1991). The theory of planned behavior. Organizational Behavior and Human Decision Processes, 50(2), 179-211. https://doi.org/10.1016/0749-5978(91)90020-T
Arksey, H., & O'Malley, L. (2005). Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8(1), 19-32. https://doi.org/10.1080/1364557032000119616
Booth, R. G., Strudwick, G., McBride, S., O'Connor, S., & Solano López, A. L. (2021). How the nursing profession should adapt for a digital future. BMJ, 373, n1190. https://doi.org/10.1136/bmj.n1190
Char, D. S., Shah, N. H., & Magnus, D. (2018). Implementing machine learning in health care: Addressing ethical challenges. New England Journal of Medicine, 378(11), 981-983. https://doi.org/10.1056/NEJMp1714229
Collins, G. S., Moons, K. G. M., Dhiman, P., Riley, R. D., Beam, A. L., Van Calster, B., Ghassemi, M., Liu, X., Reitsma, J. B., van Smeden, M., Boulesteix, A.-L., Camaradou, J. C., Celi, L. A., Denaxas, S., Denniston, A. K., Glocker, B., Golub, R. M., Harvey, H., Heinze, G., ... Logullo, P. (2024). TRIPOD+AI statement: Updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ, 385, e078378. https://doi.org/10.1136/bmj-2023-078378
Davis, F. D. (1989). Perceived usefulness, perceived ease of use, and user acceptance of information technology. MIS Quarterly, 13(3), 319-340. https://doi.org/10.2307/249008
De Gagne, J. C. (2023). The state of artificial intelligence in nursing education: Past, present, and future directions. International Journal of Environmental Research and Public Health, 20(6), 4884. https://doi.org/10.3390/ijerph20064884
Dixon-Woods, M., Cavers, D., Agarwal, S., Annandale, E., Arthur, A., Harvey, J., Hsu, R., Katbamna, S., Olsen, R., Smith, L. K., Riley, R., & Sutton, A. J. (2006). Conducting a critical interpretive synthesis of the literature on access to healthcare by vulnerable groups. BMC Medical Research Methodology, 6, 35. https://doi.org/10.1186/1471-2288-6-35
El Arab, R. A., Alshakihs, A. H., Alabdulwahab, S. H., Almubarak, Y. S., Alkhalifah, S. S., Abdrbo, A., Hassanein, S., & Sagbakken, M. (2025). Artificial intelligence in nursing: A systematic review of attitudes, literacy, readiness, and adoption intentions among nursing students and practicing nurses. Frontiers in Digital Health, 7, 1666005. https://doi.org/10.3389/fdgth.2025.1666005
El-Bassal, N. A. M., El-Sayed, A. A. I., & Elgamal, H. G. (2025). Empowering nurses in the AI era: Investigating the interplay between professionalism, AI readiness, and self-efficacy. BMC Nursing, 24, 1287. https://doi.org/10.1186/s12912-025-03896-y
Gianfrancesco, M. A., Tamang, S., Yazdany, J., & Schmajuk, G. (2018). Potential biases in machine learning algorithms using electronic health record data. JAMA Internal Medicine, 178(11), 1544-1547. https://doi.org/10.1001/jamainternmed.2018.3763
Grant, M. J., & Booth, A. (2009). A typology of reviews: An analysis of 14 review types and associated methodologies. Health Information and Libraries Journal, 26(2), 91-108. https://doi.org/10.1111/j.1471-1842.2009.00848.x
Holden, R. J., & Karsh, B.-T. (2010). The technology acceptance model: Its past and its future in health care. Journal of Biomedical Informatics, 43(1), 159-172. https://doi.org/10.1016/j.jbi.2009.07.002
Holden, R. J., Carayon, P., Gurses, A. P., Hoonakker, P., Hundt, A. S., Ozok, A. A., & Rivera-Rodriguez, A. J. (2013). SEIPS 2.0: A human factors framework for studying and improving the work of healthcare professionals and patients. Ergonomics, 56(11), 1669-1686. https://doi.org/10.1080/00140139.2013.838643
International Council of Nurses. (2023). Digital health transformation and nursing practice. https://www.icn.ch/sites/default/files/2023-08/ICN%20Position%20Statement%20Digital%20Health%20FINAL%2030.06_EN.pdf
Joo, J. Y., Liu, M. F., & Ho, M.-H. (2025). Nurses' perceptions of artificial intelligence adoption in healthcare: A qualitative systematic review. Nurse Education in Practice, 88, 104542. https://doi.org/10.1016/j.nepr.2025.104542
Karimian, G., Petelos, E., & Evers, S. M. A. A. (2022). The ethical issues of the application of artificial intelligence in healthcare: A systematic scoping review. AI and Ethics, 2, 539-551. https://doi.org/10.1007/s43681-021-00131-7
Labrague, L. J., Aguilar-Rosales, R., Yboa, B. C., & Sabio, J. B. (2023). Factors influencing student nurses' readiness to adopt artificial intelligence in their studies and their perceived barriers to accessing AI technology: A cross-sectional study. Nurse Education Today, 130, 105945. https://doi.org/10.1016/j.nedt.2023.105945
Liu, X., Cruz Rivera, S., Moher, D., Calvert, M. J., Denniston, A. K., & the SPIRIT-AI and CONSORT-AI Working Group. (2020). Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: The CONSORT-AI extension. BMJ, 370, m3164. https://doi.org/10.1136/bmj.m3164
Munn, Z., Peters, M. D. J., Stern, C., Tufanaru, C., McArthur, A., & Aromataris, E. (2018). Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach. BMC Medical Research Methodology, 18, 143. https://doi.org/10.1186/s12874-018-0611-x
National Academy of Medicine. (2025). An artificial intelligence code of conduct for health and medicine: Essential guidance for aligned action. National Academies Press. https://doi.org/10.17226/29087
National Institute of Standards and Technology. (2023). Artificial Intelligence Risk Management Framework (AI RMF 1.0) (NIST AI 100-1). https://doi.org/10.6028/NIST.AI.100-1
Pujari, S., Reis, A., Zhao, Y., Alsalamah, S., Serhan, F., Reeder, J. C., & WHO AI for Health Working Group. (2023). Artificial intelligence for global health: Cautious optimism with safeguards. Bulletin of the World Health Organization, 101(4), 290-215. https://doi.org/10.2471/BLT.23.290215
Ramadan, O. M. E., Alruwaili, M. M., Alruwaili, A. N., Elsehrawy, M. G., & Alanazi, S. (2024). Facilitators and barriers to AI adoption in nursing practice: A qualitative study of registered nurses' perspectives. BMC Nursing, 23, 891. https://doi.org/10.1186/s12912-024-02571-y
Rivera, S. C., Liu, X., Chan, A.-W., Denniston, A. K., Calvert, M. J., Ashrafian, H., Beam, A. L., Collins, G. S., Darzi, A., Deeks, J. J., Eeles, E., Haug, C., Moher, D., Ordish, J., Penzien, J., & the SPIRIT-AI and CONSORT-AI Working Group. (2020). Guidelines for clinical trial protocols for interventions involving artificial intelligence: The SPIRIT-AI extension. BMJ, 370, m3210. https://doi.org/10.1136/bmj.m3210
Tricco, A. C., Lillie, E., Zarin, W., O'Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowan, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garritty, C., ... Straus, S. E. (2018). PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467-473. https://doi.org/10.7326/M18-0850
Vasey, B., Nagendran, M., Campbell, B., Clifton, D. A., Collins, G. S., Denaxas, S., Denniston, A. K., Faes, L., Geerts, B. F., Ibrahim, M., Liu, X., Mateen, B. A., Mathur, P., McCradden, M. D., Morgan, L., Ordish, J., Rogers, C., Saria, S., Ting, D. S. W., ... McCulloch, P. (2022). Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. BMJ, 377, e070904. https://doi.org/10.1136/bmj-2022-070904
Venkatesh, V., Morris, M. G., Davis, G. B., & Davis, F. D. (2003). User acceptance of information technology: Toward a unified view. MIS Quarterly, 27(3), 425-478. https://doi.org/10.2307/30036540
Wei, Q., Pan, S., Liu, X., Hong, M., Nong, C., & Zhang, W. (2025). The integration of AI in nursing: Addressing current applications, challenges, and future directions. Frontiers in Medicine, 12, 1545420. https://doi.org/10.3389/fmed.2025.1545420
Whittemore, R., & Knafl, K. (2005). The integrative review: Updated methodology. Journal of Advanced Nursing, 52(5), 546-553. https://doi.org/10.1111/j.1365-2648.2005.03621.x
World Health Organization. (2021). Ethics and governance of artificial intelligence for health: WHO guidance. https://www.who.int/publications/i/item/9789240029200
World Health Organization. (2023). Regulatory considerations on artificial intelligence for health. https://www.who.int/publications/i/item/9789240078871
World Health Organization. (2024). Ethics and governance of artificial intelligence for health: Guidance on large multi-modal models. https://www.who.int/publications/i/item/9789240084759
World Health Organization, & International Council of Nurses. (2025). State of the world's nursing 2025: Investing in education, jobs, leadership and service delivery. https://www.who.int/publications/i/item/9789240110236
Yang, Q., Zhao, M., Yang, L., Wang, X., & Yang, C. (2026). Artificial intelligence readiness and its influencing factors among newly qualified nurses: A cross-sectional study. Frontiers in Medicine, 13, 1753024. https://doi.org/10.3389/fmed.2026.1753024
Zhou, Y., Li, Z., & Li, Y. (2021). Interdisciplinary collaboration between nursing and engineering in health care: A scoping review. International Journal of Nursing Studies, 117, 103900. https://doi.org/10.1016/j.ijnurstu.2021.103900
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Placide Mutabazi, Sixbert SANGWA (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.